Acute laryngitis and croup

Overview

Barking (seal-like) cough - defining symptom; turbulent airflow through narrowed subglottis
Hoarse voice - vocal cord mucosal inflammation
Inspiratory stridor - turbulent flow through narrowed subglottic airway
Symptoms worse at night - characteristic; key differentiator from epiglottitis
Low-grade fever - usually present but not high
No drooling, no dysphagia - important negatives distinguishing from epiglottitis
Affects children 6 months - 6 years; peak 1-2 years; more common in boys; autumn/winter
Croup vs epiglottitis
FeatureCroupEpiglottitis
CoughBarking, seal-likeNo barking cough
FeverLow-gradeHigh, toxic appearance
DroolingNoYes
VoiceHoarseMuffled 'hot potato'
Onset1-2 day coryzal prodromeRapid progression
Throat examinationNever - risk of obstructionAvoid; senior review needed

Investigations

Croup is a clinical diagnosis - no investigations required in typical presentations
Pulse oximetry - SpO2 <92% indicates hypoxia requiring oxygen
AP neck X-ray - 'steeple sign' (subglottic narrowing) if diagnosis uncertain; not routine
Lateral neck X-ray - only if epiglottitis suspected ('thumbprint sign' in epiglottitis)
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Never perform a throat examination in a child with suspected croup - direct inspection can precipitate complete airway obstruction by provoking laryngospasm.

Management

All croup: single dose oral dexamethasone 0.15 mg/kg regardless of severity
If oral not tolerated: nebulised budesonide; if dexamethasone unavailable: oral prednisolone 1 mg/kg
Step 1 · All croup
  1. 1Oral dexamethasone 0.15 mg/kg (single dose)
  2. 2Corticosteroids reduce subglottic oedema within 1-6 hours
Mild - no stridor at rest, no recession
Discharge with safety netting advice
Moderate - stridor at rest, no agitation/recession
Give dexamethasone + urgent hospital admission
Severe - stridor at rest + agitation/recession, SpO2 <92%, or signs of exhaustion
Hospital admission + nebulised adrenaline (temporising) + oxygen if SpO2 <92%
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Nebulised adrenaline is reserved for severe croup only - it is a temporising measure (effect lasts 1-2 hours, rebound possible). Any child receiving it must be admitted and observed for at least 2-4 hours.
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Dexamethasone dose calculation: 0.15 mg/kg. A 12 kg child = 1.8 mg. A 10 kg child = 1.5 mg.
Acute laryngitis (adults): voice rest, hydration, avoid smoking/alcohol - no antibiotics (almost always viral)
Hoarseness persisting >3 weeks in an adult - urgent referral to exclude laryngeal malignancy
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A child with severe croup who is tiring may show paradoxically reduced recession - not improvement, but respiratory muscle fatigue. RR >70/min, pallor, cyanosis, or falling consciousness are signs of impending respiratory failure.